Biohacking

A Look at Biohacking

One of the terms that have evolved in the health and fitness field that I really dislike is biohacking. Whether related to fitness, nutrition, or supplementation, the implication is that there are shortcuts to get health benefits. I believe that we can do things that are a more efficient use of time but when it comes to your health, there are no shortcuts. If you want benefits, you have to put in the effort. This week, I’m going to give you an example of a reasonable idea that hasn’t proven to demonstrate the benefits that were expected.

The concept for the polypill was introduced 15 years ago. The purpose was to put together a group of medications that could help reduce the risk of cardiovascular disease (CVD) by giving it to everyone over 55. The polypill was modified over the years to include low doses of aspirin, a statin, beta-blocker, angiotensin-converting enzyme (ACE) inhibitor, diuretic, and folic acid or some combination of these medications. The idea was that putting all the medications together in a single pill would increase adherence, a significant issue when it comes to taking medications. By so doing, it would decrease the risk of CVD disease.

The polypill has not been put into use in the U.S. While there are some positive data from other countries, the clinical trials that have been done are not long enough to demonstrate reduction in mortality and CVD events. But a recent study on one component of that polypill shows that it may not be such a good idea for everyone. I’ll continue on Thursday.

What are you prepared to do today?

Dr. Chet